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Which Ellutia instrument do I need for nitrosamine testing?

 

The answer depends on what type of result you need and where you are in your testing workflow.

I need to screen large numbers of samples for total nitrosamine content

Use the Automated Total Nitrosamine Analyser (ATNA). It measures total nitrosamines as a single value without identifying individual compounds. It processes up to 10 samples per hour from a 120-vial autosampler and runs unattended. Sensitivity is below 1 ppb. No gas chromatograph is required.

The ATNA is the right starting point for incoming raw material checks, excipient screening, cosmetics compliance testing against the EU 50 μg/kg limit, and any application where you need to know whether nitrosamines are present before deciding if further analysis is needed.

I need to identify and quantify specific nitrosamine compounds

Use a GC-TEA configuration. A gas chromatograph (200 Series or 500 Series) separates the sample, and the 800 Series TEA detects and quantifies each nitrosamine individually. This gives you compound-specific concentrations for regulatory reporting under frameworks such as ICH M7.

GC-TEA is used for pharmaceutical impurity testing, confirmatory analysis on samples flagged by screening, trace explosives detection, and any application where you need to know which nitrosamines are present and at what levels.

I need to monitor airborne nitrosamines in a workplace

Use the ThermoSorb-N air sampling cartridge. It collects airborne nitrosamines without the artifact formation problems associated with other sorbents. After sampling, the cartridge is analysed by GC-TEA.

I need to screen and confirm

Many laboratories use the ATNA and GC-TEA together. The ATNA screens everything. Samples that pass are cleared. Samples that flag move to GC-TEA for speciated analysis. This is the most efficient workflow for high-volume testing.

I am not sure yet

Get in touch with your application details and we can recommend the right instrument or combination for your specific testing requirements.